Some people are searching for treatment options and may encounter items not being prescribed, or removed from their prescription. We hope the following helps explain things:

The British National Formulary (BNF) is a national formulary in the UK which is updated every 6-12 months and available on-line for prescribers.

Local and regional formularies exist throughout the UK which are developed and up-dated by the local and regional Drugs and Therapeutics Committees. These committees select products from the BNF and place them on an agreed local/regional formulary for prescribers to follow.

A medical and non-medical independent prescriber has a qualification to be able to prescribe products listed in the British National Formulary (BNF) that is within their scope of practice.

It is expected that prescribers follow the recommendations of the local formulary ensuring efficacy and cost optimisation wherever possible. For example, 80% of medicines prescribed should be on the approved local/regional formulary. Deviation from the local formulary (i.e. 20% Off-formulary products) is at the discretion of the independent prescriber and individual clinical situation.

The most efficacious and cost effective emollient are the ones patients will apply regularly. It is not cost effective or clinically efficacious to prescribe products that the patients dislike or are reluctant to apply.

Many people with ichthyosis ask us about products containing urea.

Current Urea containing products listed in BNF are:

Source: BNF (last accessed 15 April 2025)

Product
% Urea
Company
Cost 500gm NHS
Balneum Plus cream 5% Almirall Ltd £14.99
E45 Itch Relief cream 5% Karo Healthcare UK Ltd £17.77
Aquadrate cream  10%  Alliance Pharmaceuticals (100g x5) £23.30
Eucerin Urea Repair Plus foot cream 10%  Beiersdorf UK Ltd (100ml x5) £28.75
Flexitol 10% Urea cream 10% Thornton & Ross Ltd £12.54
Hydromol Intensive 10% cream 10% Alliance Pharmaceuticals Ltd (100gx5)  £23.30
Udrate Cream (Urea/Lactic Acid) 10%/5% Ennogen Healthcare International Ltd (100g x5) £64.45
Flexitol Heel Balm cream 25% Thornton & Ross Ltd £15.77

Some products available for use in treating ichthyosis are as follows:

Moisturisers                                       Largest Product Size Available         Manufacturer

Aqueous Cream                                  500g                                                    Proprietary

Aveeno Cream                                    100ml                                                  Kenvue UK Ltd

Cetraben range                                   500g                                                    Thornton and Ross

Dermol range                                      500ml                                                   Dermal

Dexeryl                                                250g                                                   Pierre Fabre

Diprobase Cream                                500g                                                   Dendron Brands Ltd 

Doublebase range                               500ml                                                 Dermal

E45 Cream                                          500g                                                   Karo Healthcare UK Ltd 

Emollin (Spray)                                    250ml                                                 CD Medical

Epaderm range                                   500g                                                    Molnlycke Healthcare

Epimax range                                      500g                                                    Aspire Pharma UK

Lipobase Cream                                  50g                                                      Karo Healthcare UK Ltd 

Neutrogena Dermatological

Cream                                                100g                                                    Johnson & Johnson

Oilatum Cream                                   500ml                                                  Thornton & Ross

QV range                                            500g                                                    Ego Pharmaceuticals

Ultrabase Cream                                500g                                                    Derma UK

Unguentum M Cream                         500g                                                    Almirall 

Vaseline Dermacare Cream               150ml                                                  Elida Faberge

White Soft Paraffin/

Liquid Paraffin (50/50)                           500g                                                     Proprietary

 

Bath Oils                                             Largest Product Size Available         Manufacturer

Alpha Keri                                           480ml                                                  Westwood

Aveeno Bath Emollient                       250ml                                                  Johnson and Johnson

Aveeno Collodial                                 Sachets                                               Kenvue

Balneum Bath Oil                               500ml                                                   Almirall

Balneum Plus Bath Oil                        500ml                                                  Almirall

Dermol                                                500ml                                                  Dermal

Diprobath                                            500ml                                                  Schering-Plough

E45 Bath Oil                                        500ml                                                  Crookes Healthcare

Emulsiderm                                         1L                                                        Dermal

Epimax                                                500ml                                                  Aspire 

Hydromol                                            1L                                                        Alliance

Imuderm*                                           250ml                                                   Clinisupplies

Infaderm                                             250ml                                                  Ceuta

Oilatum range                                    500ml                                                  Thornton and Ross

QV range                                           500ml                                                   Ego Pharmaceuticals

 

Scalp Treatments                               Largest Product Size Available         Manufacturer

Capasal                                                250ml                                                   Dermal

Cocois*                                                100g                                                     UCB

Dermax*                                             250ml                                                    Dermal

Nizoral Shampoo                                 120ml                                                  Thornton & Ross

Olive Oil                                              Readily available

Polytar range                                     500ml                                                    Thornton & Ross

Salicylic acid preparations                                                                              Consult your doctor

Sebco*                                                  100g                                                  Derma UK

 

How Greasy are the Products?

Very Greasy                            Greasy                                     Less Greasy                 Mild

White Soft Paraffin/                Ungeuntum                             Aveeno Cream            Aqueous Cream

Liquid Paraffin (50/50)           Merck Cream                          Dermol Lotion

Hydrous Ointment                  Neutrogena                             Diprobase Cream

Diprobase Ointment               Dermatogical                          E45 Cream

Dermamist Spray*                  Cream                                     Ultrabase Cream

Epaderm                                 Oilatum Cream                       Lipobase Cream

Hydromol cream                     Cetraben Cream        

Vaseline                                  Alcoderm Cream/lotion         

Dermacare                              Doublebase

Cream

Please note the products denoted with a * contain nut oil/s.                                                     

Sunscreens

Always use a high factor sunscreen product e.g. 25,25, 50. Those formulated for children and for sensitive skin are more suited for more ‘fragile’ skin. You should always patch test a product – ask the chemist if they have any samples you could try before purchasing a sunscreen product. A small number of the companies listed in this leaflet produce sunscreen products. Some brands are available on prescription e.g. E45 or Uvistat.

As with any products, moisturisers, bath oils etc are discontinued and new products manufactured constantly and this list is not an exhaustive list of all the products used in the treatment of ichthyosis. Product licences change resulting in different companies manufacturing and/or distributing products. Please ask your pharmacist about the range of products available.

This information is for advice only, please consult your doctor before altering any treatments.

 

Download The Treatments Used in Ichthyosis Factsheet

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